During the mission "TR_m4_IL_giveledger" the topic "Raynil's Ledger" was missing for me so I could not give the ledger to Mette-Black Briar in the East Empire Company in Old Ebonheart.
The command addTopic "Raynil's Ledger" did the trick.
I assume the topic was not properly enabled during the previous quest "TR_m4_IL_Agent"

I don't know where the topic is supposed to be added but I checked the script (TR_m4_IL_Bookscript) of the ledger item itself (TR_m4_IL_Moriobook)
and was not able to find the addTopic command there if the player takes the book.

If you could tell me where the topic is supposed to be added I could play through the quest again and see if I can reliable reproduce the behaviour.